SCIENCE

Applied - Medicine
Most Expensive Prescription Drugs
This list features the most expensive prescription drugs based on annual treatment costs as of 2022.
RANK | DRUG | ANNUAL TREATMENT COST | MANUFACTURER | DESCRIPTION |
1 | Zolgensma | $2,125,000 | Novartis (Switzerland) | A gene therapy for spinal muscular atrophy (SMA), a genetic disorder affecting muscle strength. |
2 | Zokinvy | $1,032,480 | Eiger BioPharmaceuticals (USA) | Treatment for progeria, a rare genetic condition causing rapid aging in children. |
3 | Luxturna | $850,000 | Novartis (Switzerland) | Gene therapy for Leber congenital amaurosis, a rare genetic disease causing blindness. |
4 | Ravicti | $794,000 | Horizon Pharma GmbH (Germany) | Used for treating urea cycle disorders, which prevent the body from removing ammonia. |
5 | Carbaglu | $790,000 | Recordati (Italy) | A treatment for acute hyperammonemia in patients with certain urea cycle disorders. |
6 | Soliris | $700,000 | Alexion Pharmaceuticals Inc. (USA) | A complement inhibitor used to treat various rare blood disorders, including PNH and aHUS. |
7 | Brineura | $700,000 | BioMarin Pharmaceutical Inc. (USA) | Enzyme replacement therapy for Batten disease, a rare neurodegenerative disorder in children. |
8 | Elaprase | $657,000 | The Shire (Ireland) | Enzyme replacement therapy for Hunter syndrome, a genetic disorder affecting metabolism. |
9 | Lumizyme | $520,000 | Sanofi Genzyme (USA) | Treatment for Pompe disease, a rare genetic disorder that affects muscle function. |
10 | Spinraza | $375,000 | Biogen (USA) | An antisense oligonucleotide used to treat spinal muscular atrophy (SMA). |
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